Best choice for more severe facial wrinkles 

Just like Restylane®Perlane is a clear gel formulation of hyaluronic acid that is specifically formulated to act like your body's own hyaluronic acid, adding volume and fullness to the skin.

Before After

Perlane used to perform Non-Surgical Nose Job, Before and After

Perlane injected into nasolabial folds (smile lines), Before and after. 31 year old female

Perlane injected into nasolabial folds (smile lines), Before and after. 31 year old female

What are Restylane & Perlane and what do they do?

Restylane® & Perlane® are FDA-approved cosmetic dermal fillers from Medicis. They are both composed of hyaluronic acid—a naturally occurring substance in your body that helps to provide fullness and elasticity. Over time, skin loses natural hyaluronic acid, but injections of dermal fillers like Restylane® & Perlane® are able to help fill the wrinkles and folds caused by this.

The difference between Restylane® & Perlane® is their particle size. Perlane® has larger gel particles and is intended to be injected deeper within the skin.

For more information on Restylane® & Perlane®, including all FDA information and a catalog of before and after photos, please visit the Medicis Restylane® & Perlane® website at

Where are Restylane & Perlane used?

Restylane® & Perlane® are used most often in the nasolabial folds (the parentheses from your nose to the corners of your mouth), under the eyes and in the upper cheeks, and in the lips. Depending upon the site of injection and your specific volume loss, multiple syringes may be needed for full effects. If patients are truly unhappy with a hyaluronic acid filler (like Restylane® or Perlane®, or if an error has been made with an injection,) the filler itself can be destroyed with the injection of Vitrase/hyaluronidase.

What are Restylane & Perlane treatments like?

As with all filler injections, Restylane® & Perlane® are only injected by Dr. Alnajjar. He will begin by discussing the treatment with you and have you sign a consent for the procedure. Dr. Alnajjar will prep the site with a lidocaine/epinephrine block to further reduce any pain or discomfort during the procedure and have you wait about 10 minutes. (Both Restylane® & Perlane® have recently launched a different version of their injectables which already contain Lidocaine in the syringe, premixed from the company. Because the compound doesn't contain epinephrine though, Dr. Alnajjar still prefers to do his own block as it's more beneficial to each patient and reduces bruising and swelling.) By waiting this amount of time, the blood flow to that area is able to dissipate a bit, resulting in less bruising and swelling. After about 10 minutes, Dr. Alnajjar will administer the Restylane® or Perlane® syringe and expertly and artistically inject the substance into the areas to be filled and revolumized. Dr. Alnajjar will apply ice packs to the injected areas and have you sit for a few minutes to apply pressure, thereby further minimizing swelling and bruising. The full procedure should take approximately 30-45 minutes. You will leave the office having minimal discomfort or other affects and be able to return to normal activities.

What kind of results can I expect from a Restylane or Perlane treatment?

You should see an immediate improvement in the treatment areas (normally 1-2 days) with minimal bruising or swelling. Sometimes bruising and swelling can be minimized by taking Arnica pills, using Arnica gel, or having Arnica gel pads applied post procedure. Arnica is a natural medication that can be obtained from a local health foods store. It is not necessary to take it, but some people find it helpful, particularly if they are prone to bruising. Ice packs and avoidance of aspirin for a few days will help should you encounter either of these as well. Restylane® & Perlane® will help fill, smooth, and minimize the lines, wrinkles, and/or folds into which it is injected. For most patients, Restylane® lasts approximately 6-8 months, and Perlane® approximately 8-10 months, although in some cases and areas, the duration of the effect may be shorter or longer. Supplemental treatments may be required to achieve and maintain optimal results.